Intrauterine Insemination (IUI) is a fertility treatment that involves placing washed spermatozoa into the uterine cavity in order to increase the chance of fertilization.
The IUI procedure consists of five steps:
- Egg Stimulation: Fertility drugs are administered to stimulate the growth of one or two eggs to maturity. Oral tablets such as Clomid/Letrozole or daily injections such as Gonal-F//Menopur/ are used to enlarge the follicles that cause ovulation to occur.
- Ultrasound and Blood Monitoring: Ultrasound is done at intervals of several days to monitor the ovaries and egg development. Blood tests are also completed to assess hormone levels related to egg growth and ovarian function.
- Ovulation Induction: When the leading follicle(s) reaches an average diameter of 18-20 mm, the last trigger injection (Ovitrelle) is administered and the IUI is scheduled 36-40 hours later.
- Insemination: The washed and concentrated sperm sample is loaded into a catheter and placed into the uterus with a filled bladder under trans-abdominal ultrasonography. IUI is an outpatient procedure that does not require anesthesia. IUI is fairly painless procedure.
- Pregnancy Test: A pregnancy test is done 2 weeks after the IUI procedure. It is important to follow the doctor’s directions in the process up to the pregnancy test.
The chance of success is higher in women who menstruate regularly, whose tubes are open and who do not have endometriosis and are below 35. The chance of pregnancy with inoculation is around 15-20% in each application. Up to 3 cycles of IUI might be considered. However, if pregnancy is not achieved with the IUI method, IVF can be planned. IUI is a less invasive and less expensive option compared to IVF.
You may be a good candidate for IUI if:
• Your partner has sufficient sperm count
• You have mild to moderate endometriosis
• You have problems with cervical mucus
• You are allergic to semen
• You have healthy hormone levels
• You have healthy fallopian tubes that are not blocked
• You have a sufficient number of quality eggs in her ovaries
You may not be a suitable candidate for IUI if:
You have severe endometriosis
You have tubal disease
• You have an insufficient number of quality eggs in your ovaries
• You have a history of pelvic adhesions
• You have attempted IUI three times in the past without success
• Your partner has low sperm count with otherwise healthy sperm
• Your partner has low sperm motility with otherwise healthy sperm
consultation and evaluation with obstetrician–gynecologist
All monitoring ultrasound scans within the cycle
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